BDBM50666006 CHEMBL6162182

SMILES CN(C)C(=O)c1ccc(-c2n[nH]c3ncc(-c4ccc5c(c4)CC[C@@H](N4C6COCC4C6)CC5)cc23)cc1

InChI Key InChIKey=ZUFHZMHKCFCIHV-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666006   

TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666006BDBM50666006(CHEMBL6162182)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human AXL measured after 150 mins by ATP-competitive HTRF based biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666006BDBM50666006(CHEMBL6162182)
Affinity DataKd:  6.80nMAssay Description:Binding affinity to AXL (unknown origin) expressed in HEK293 cells transfected with Nano-Luc fusion vector assessed as dissociation constant by measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed