BDBM50665977 CHEMBL6171513

SMILES COCc1cc(Cl)c(-n2cnc(N)c(C(=O)Nc3cncc(C(N)COC)c3)c2=O)c(Cl)c1

InChI Key InChIKey=ZGDFRKITUQJDBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50665977   

TargetGlycogen synthase kinase-3 alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665977BDBM50665977(CHEMBL6171513)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human GSK3alpha extracted from baculovirus expression system using 5-FAM-KRREILSRRPpSYR-COOH as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665977BDBM50665977(CHEMBL6171513)
Affinity DataIC50: 123nMAssay Description:Inhibition of full length human GSK3beta extracted from baculovirus expression system using 5-FAM-KRREILSRRPpSYR-COOH as substrate preincubated for 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665977BDBM50665977(CHEMBL6171513)
Affinity DataIC50: 155nMAssay Description:Inhibition of Nanoluc-GSK2beta (unknown origin) expressed in HEK293 cells measured after overnight incubation by NanoBRET- cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed