BDBM50665946 CHEMBL6167507

SMILES C[C@@](O)(CS(N)(=O)=O)c1ccc(F)c(-c2nnn(Cc3cc(OC(F)(F)F)ccc3F)n2)c1

InChI Key InChIKey=PUPYHRCTLUFTAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50665946   

TargetSodium channel protein type 5 subunit alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665946BDBM50665946(CHEMBL6167507)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.5 expressed in CHO-K1 cells preincubated for 3 mins followed by incubation under atrial fibrillation-mimicking condition at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665946BDBM50665946(CHEMBL6167507)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO-K1 cells preincubated with compound for 3 mins in presence of ATXII followed by incubation under ventricu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665946BDBM50665946(CHEMBL6167507)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO-K1 cells preincubated for 3 mins followed by incubation under ventricular condition at sinus rate at 1 Hz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed