BDBM50665740 CHEMBL6167864

SMILES CC1(F)CN(C(=O)Cn2cnc3sc(C#N)c(-c4ccc(F)c(Br)c4)c3c2=O)C1

InChI Key InChIKey=RGDROOXSGYKNIT-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50665740   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665740BDBM50665740(CHEMBL6167864)
Affinity DataEC50:  360nMAssay Description:Positive allosteric modulation of recombinant rat GluN2B receptor expressed in Xenopus oocytes assessed as glutamate/glycine-induced potentiation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665740BDBM50665740(CHEMBL6167864)
Affinity DataEC50:  890nMAssay Description:Positive allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus oocytes assessed as glutamate/glycine-induced potentiation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665740BDBM50665740(CHEMBL6167864)
Affinity DataEC50:  940nMAssay Description:Positive allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus oocytes assessed as glutamate/glycine-induced potentiation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed