BDBM50665627 CHEMBL6170180

SMILES Cc1c(-c2cc(-c3ccc(F)cc3F)cc3c2CNC3=O)cnn1C

InChI Key InChIKey=PQDKFTZZJLDEPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50665627   

TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665627BDBM50665627(CHEMBL6170180)
Affinity DataIC50: 58nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665627BDBM50665627(CHEMBL6170180)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed