BDBM50665193 CHEMBL6143086

SMILES CCCCCCCNCc1c(-c2ccccc2)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=NTXITOPQAGVYKU-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50665193   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665193BDBM50665193(CHEMBL6143086)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human 15-LOX-1 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665193BDBM50665193(CHEMBL6143086)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human 15-LOX-1 using linoleic acid as substrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665193BDBM50665193(CHEMBL6143086)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human 15-LOX-1 using linoleic acid assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed