BDBM50664766 CHEMBL6149258

SMILES NS(=O)(=O)c1ccc(-n2ncc(NC(=O)Nc3ccc(F)cc3)c2-c2ccccc2)cc1

InChI Key InChIKey=QBHGUUZZUZWKFY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50664766   

TargetCarbonic anhydrase 9(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664766BDBM50664766(CHEMBL6149258)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664766BDBM50664766(CHEMBL6149258)
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664766BDBM50664766(CHEMBL6149258)
Affinity DataKi:  51nMAssay Description:Inhibition of human recombinant CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664766BDBM50664766(CHEMBL6149258)
Affinity DataKi:  4.81E+4nMAssay Description:Inhibition of human recombinant CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed