BDBM50663975 CHEMBL6168739

SMILES CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(CCCCCCCC(=O)NO)CC3)c(OC)c2)nc1NC1CCOCC1

InChI Key InChIKey=DHHLNBBLQAWSMH-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50663975   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FLT3 (unknown origin) incubated for 40 mins in presence of ATP by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC6 in human HeLa nuclear extract using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC3 in human HeLa nuclear extract using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 121nMAssay Description:Inhibition of HDAC10 in human HeLa nuclear extract using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 145nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 199nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extract using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 425nMAssay Description:Inhibition of HDAC8 in human HeLa nuclear extract using Boc-Lys (TFA)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of HDAC4 in human HeLa nuclear extract using Leu-Gly-Lys (TFA)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of HDAC7 in human HeLa nuclear extract using Leu-Gly-Lys (TFA)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC9 in human HeLa nuclear extract using Leu-Gly-Lys (TFA)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC5 in human HeLa nuclear extract using Leu-Gly-Lys (TFA)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663975BDBM50663975(CHEMBL6168739)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC11 in human HeLa nuclear extract using Ac-Leu-Gly-Lys(Ac)-AMC as substrate incubated for 0.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed