BDBM50663357 CHEMBL6164838
SMILES O=C(Nc1nccs1)c1cccc2[nH]c(-c3ccc(OC(F)F)c(OCC4CC4)c3)nc12
InChI Key InChIKey=SYPSQPSGJSOJEB-UHFFFAOYSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50663357
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PDE4D (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of PDE4B (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of PDE4A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE1A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE11A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE8A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE9A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5A (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE6C (unknown origin) using FAM-cAMP as substrate preincubated with compound for compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair