BDBM50663293 CHEMBL6167397

SMILES CN(O)C(=O)CSC(c1ccc(OCCCCCCN2C(=O)c3ccccc3C2=O)cc1)P(=O)(O)O

InChI Key InChIKey=KKTRNDWKNMCAEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50663293   

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663293BDBM50663293(CHEMBL6167397)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant Escherichia coli DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photometric assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663293BDBM50663293(CHEMBL6167397)
Affinity DataIC50: 21nMAssay Description:Inhibition of Plasmodium falciparum DXR extracted from Escherichia coli using DXP as substrate by NADPH consumption based photometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663293BDBM50663293(CHEMBL6167397)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed