BDBM50663014 CHEMBL6164049
SMILES CN1CCN(C(=O)c2ccc(NC(=S)Nc3ccc(-c4nc(N5CCOCC5)nc(N5CCOCC5)n4)cc3)cc2)CC1
InChI Key InChIKey=QGDPDCRKNPZQHV-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50663014
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiujiang University
Curated by ChEMBL
Jiujiang University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 as substrate measured after 45 mins in presence of ATP by Lance ultra assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Jiujiang University
Curated by ChEMBL
Jiujiang University
Curated by ChEMBL
Affinity DataIC50: 169nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Jiujiang University
Curated by ChEMBL
Jiujiang University
Curated by ChEMBL
Affinity DataIC50: 338nMAssay Description:Inhibition of PI3K delta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Jiujiang University
Curated by ChEMBL
Jiujiang University
Curated by ChEMBL
Affinity DataIC50: 657nMAssay Description:Inhibition of PI3K gamma (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assayMore data for this Ligand-Target Pair