BDBM50662635 CHEMBL6170558

SMILES C[C@H](NC(=O)c1csc(-c2ccc(S(C)(=O)=O)cc2)n1)c1cn(-c2cc(C(F)(F)F)ccn2)nn1

InChI Key InChIKey=JNJCBWJLPVNKQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662635   

TargetP2X purinoceptor 7(Mouse)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662635BDBM50662635(CHEMBL6170558)
Affinity DataIC50: 99nMAssay Description:Antagonist activity against mouse P2X7 receptor expressed in ATP-stimulated HEK293 cells assessed as influx of PI by fluorescence dye uptake assay re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662635BDBM50662635(CHEMBL6170558)
Affinity DataIC50: 192nMAssay Description:Antagonist activity against human P2X7 receptor expressed in ATP-stimulated HEK293 cells assessed as influx of PI by fluorescence dye uptake assay re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed