BDBM50662629 CHEMBL6174470

SMILES CS(=O)(=O)c1ccc(-c2ncc(C(=O)NCc3cn(-c4cc(N5CCC(F)(F)CC5)ccn4)nn3)s2)cc1

InChI Key InChIKey=HLSBQNKYFKVCCO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662629   

TargetP2X purinoceptor 7(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662629BDBM50662629(CHEMBL6174470)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against human P2X7 receptor expressed in ATP-stimulated HEK293 cells assessed as influx of PI by fluorescence dye uptake assay re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetP2X purinoceptor 7(Mouse)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662629BDBM50662629(CHEMBL6174470)
Affinity DataIC50: 61nMAssay Description:Antagonist activity against mouse P2X7 receptor expressed in ATP-stimulated HEK293 cells assessed as influx of PI by fluorescence dye uptake assay re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed