BDBM50661307 CHEMBL6161308

SMILES COc1cc(F)ccc1Oc1ncc(C(F)(F)F)cc1C(=O)Nc1cccc(S(C)(=O)=O)c1

InChI Key InChIKey=UOFJFRGJQVYXQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50661307   

TargetSodium channel protein type 10 subunit alpha(Human)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661307BDBM50661307(CHEMBL6161308)
Affinity DataIC50: 14nMAssay Description:Inhibition of human Nav1.8 with resting membrane potential at half inactivated state by PatchXpress high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661307BDBM50661307(CHEMBL6161308)
Affinity DataIC50: 60nMAssay Description:Inhibition of Nav1.8 (unknown origin) over expressed in HEK cells assessed as reduction in deltamethrin-stimulated channel activation by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed