BDBM50661190 CHEMBL6165720

SMILES COc1cnc(-c2cc3ccn(C[C@H](F)C[C@H](C)Oc4cn[nH]c(=O)c4C(F)(F)F)c(=O)c3c(F)c2F)nc1

InChI Key InChIKey=RPUNMMFXRPQYLD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50661190   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661190BDBM50661190(CHEMBL6165720)
Affinity DataEC50:  0.375nMAssay Description:Inhibition of PARP7 in human NCI-H1373 cells assessed as increase in STAT1 phosphorylation at Tyr701 incubated for 48 hrs by LANCE Ultra sandwich ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed