BDBM50660948 CHEMBL6163291

SMILES C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CCCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=YVACCDYMBYQRTM-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50660948   

TargetSuppressor of tumorigenicity 14 protein(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660948BDBM50660948(CHEMBL6163291)
Affinity DataKi:  0.160nMAssay Description:Inhibition of Matriptase (unknown origin) assessed as inhibition constant using Boc-QAR-AMC as substrate incubated for 1 hr by fluorescence based ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660948BDBM50660948(CHEMBL6163291)
Affinity DataKi:  0.530nMAssay Description:Inhibition of recombinant das TMPRSS2 (unknown origin) extracted from baculovirus infected in Sf9 cells assessed as inhibition constant using Boc-QAR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660948BDBM50660948(CHEMBL6163291)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant TMPRSS2 (unknown origin) extracted from baculovirus infected in Sf9 cells using Boc-QAR-AMC as substrate measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660948BDBM50660948(CHEMBL6163291)
Affinity DataKi:  33nMAssay Description:Inhibition of TMPRSS2 (unknown origin) assessed as inhibition constant using Boc-RRVR-AMC as substrate incubated for 1 hr by fluorescence based analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed