BDBM50660682 CHEMBL6162015

SMILES COc1nc(-c2cc(-c3cnn(C)c3)cnc2N)cc2c1C(=O)N(CC(F)(F)F)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50660682   

TargetSerine/threonine-protein kinase SIK2(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 85nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 230nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Lck(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 326nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCyclin-G-associated kinase(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 492nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 586nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 594nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase ULK2(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 2.08E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Insilico Medicine Shanghai Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660682BDBM50660682(CHEMBL6162015)
Affinity DataIC50: 2.66E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed