BDBM50660515 CHEMBL6174060

SMILES COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)c3nc4ccccc4s3)cc12

InChI Key InChIKey=NUJUFUAPUGHGAK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50660515   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660515BDBM50660515(CHEMBL6174060)
Affinity DataKi:  17nMAssay Description:Inhibition of SARS-CoV-2 MPro assessed as inhibition constant in presence of TCEP by FRET-based substrate cleavage assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660515BDBM50660515(CHEMBL6174060)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant SARS-CoV-2 MPro in presence of TCEP by FRET-based substrate cleavage assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed