BDBM50660425 CHEMBL6152856

SMILES Nc1nc(-c2ccc(CNC(=O)Cc3ncc(NS(=O)(=O)c4ccccc4)cn3)cc2)c[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50660425   

TargetMannan-binding lectin serine protease 2(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetUrokinase-type plasminogen activator(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 7.41E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetPlasminogen(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 8.90E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGranzyme A(Homo sapiens)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetProthrombin(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTissue-type plasminogen activator(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGranzyme K(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine protease hepsin(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCoagulation factor VII(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTransmembrane protease serine 6(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetPlasma kallikrein(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine protease 27(Homo sapiens)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCoagulation factor IX(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetProstasin(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCoagulation factor X(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetComplement C1s subcomponent(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCoagulation factor XI(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCathepsin G(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660425BDBM50660425(CHEMBL6152856)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed