BDBM50660395 CHEMBL6132637

SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)Nc1nc(N)ccc1/N=N/c1ccccc1

InChI Key InChIKey=OSBQDQFZPRVCJV-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50660395   

TargetReplicase polyprotein 1ab(2019-nCoV)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660395BDBM50660395(CHEMBL6132637)
Affinity DataEC50:  1.11E+3nMAssay Description:Inhibition of his tagged SARS-CoV-2 nsp12 in HEK-293T cells cotransfected with pCoV-GLuc incubated for 24 hrs in the presence of coelenterazine-h by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660395BDBM50660395(CHEMBL6132637)
Affinity DataEC50:  1.36E+3nMAssay Description:Inhibition of SARS-CoV-2 nsp14 in HEK-293T cells cotransfected with pCoV-GLuc incubated for 24 hrs in the presence of coelenterazine-h by Gaussia luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660395BDBM50660395(CHEMBL6132637)
Affinity DataKd:  2.41E+3nMAssay Description:Binding affinity to SARS-CoV-2 nsp12 expressed in Escherichia coli BL21 (DE3) cells using biotinylated EZ-link NHS-LC-LC assessed as dissociation con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed