BDBM50660364 CHEMBL6173614

SMILES Cc1cc(C)c(S(=O)(=O)N(CC(=O)O)c2ccc(N[C@@H](C)CC(=O)O)c3ccccc23)c(C)c1

InChI Key InChIKey=DAJQMPGMTNIDEM-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50660364   

TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660364BDBM50660364(CHEMBL6173614)
Affinity DataKd:  500nMAssay Description:Binding affinity to Keap1 kelch domain (322 to 609 residues) (unknown origin) assessed as dissociation constant at 300 uM by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660364BDBM50660364(CHEMBL6173614)
Affinity DataKd:  530nMAssay Description:Binding affinity to Keap1 kelch domain (322 to 609 residues) (unknown origin) assessed as dissociation constant by BLI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660364BDBM50660364(CHEMBL6173614)
Affinity DataIC50: 550nMAssay Description:Inhibition of Keap1 kelch domain (322 to 609 residues) (unknown origin)/Nrf2 (unknown origin) protein-protein interaction incubated for 30 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed