BDBM50660198 CHEMBL6148250

SMILES CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCCC[C@H](NC(C)=O)C(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)N4CCC[C@H]4C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc4cncn4CCCCCCCCc4ccccc4)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O)cc3OC)nc2N1C1CCCC1

InChI Key InChIKey=LFPFALJJIGIMRZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50660198   

TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660198BDBM50660198(CHEMBL6148250)
Affinity DataIC50: 1.90nMAssay Description:Displacement of FITC-miniPEG-PLH*SpT from full length Plk1 (unknown origin) preincubated for 30 mins followed by fluorescent probe addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660198BDBM50660198(CHEMBL6148250)
Affinity DataIC50: 5.40nMAssay Description:Displacement of FITC-miniPEG-FDPPLHSpTA from full length Plk1 (unknown origin) preincubated for 30 mins followed by fluorescent probe addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660198BDBM50660198(CHEMBL6148250)
Affinity DataIC50: 41nMAssay Description:Displacement of biotin-Ahx-PMQSpTPLN from myc-tagged Plk1 in cytosolic lysates (unknown origin) preincubated for 1 hr followed by biotinylated probe ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660198BDBM50660198(CHEMBL6148250)
Affinity DataIC50: 90nMAssay Description:Inhibition of Plk1 (unknown origin) using peptide-based substrate by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed