BDBM50660195 CHEMBL6146666

SMILES CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCCC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc4cncn4CCCCCCCCc4ccccc4)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]4CCCN4C(C)=O)[C@@H](C)OP(=O)(O)O)C(N)=O)cc3OC)nc2N1C1CCCC1

InChI Key InChIKey=RUMQYEUDCFUZCJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50660195   

TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660195BDBM50660195(CHEMBL6146666)
Affinity DataIC50: 1.80nMAssay Description:Displacement of FITC-miniPEG-PLH*SpT from full length Plk1 (unknown origin) preincubated for 30 mins followed by fluorescent probe addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660195BDBM50660195(CHEMBL6146666)
Affinity DataIC50: 4.90nMAssay Description:Displacement of FITC-miniPEG-FDPPLHSpTA from full length Plk1 (unknown origin) preincubated for 30 mins followed by fluorescent probe addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660195BDBM50660195(CHEMBL6146666)
Affinity DataIC50: 41nMAssay Description:Displacement of biotin-Ahx-PMQSpTPLN from myc-tagged Plk1 in cytosolic lysates (unknown origin) preincubated for 1 hr followed by biotinylated probe ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660195BDBM50660195(CHEMBL6146666)
Affinity DataIC50: 57nMAssay Description:Inhibition of Plk1 (unknown origin) using peptide-based substrate by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed