BDBM50660069 CHEMBL6162644

SMILES CN(C(=O)N[C@@H]1COCC1(F)F)[C@H]1CCCOc2cnccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50660069   

TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660069BDBM50660069(CHEMBL6162644)
Affinity DataKd:  39nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Rattus norvegicus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660069BDBM50660069(CHEMBL6162644)
Affinity DataIC50: 226nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660069BDBM50660069(CHEMBL6162644)
Affinity DataIC50: 288nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Mus musculus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660069BDBM50660069(CHEMBL6162644)
Affinity DataIC50: 363nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660069BDBM50660069(CHEMBL6162644)
Affinity DataIC50: 402nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660069BDBM50660069(CHEMBL6162644)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed