BDBM50660042 CHEMBL6146508

SMILES C[C@@H](c1ccncc1)N(C)C(=O)N[C@@H]1COCC1(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50660042   

TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Rattus norvegicus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Affinity DataIC50: 253nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Affinity DataIC50: 285nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNAD(+) hydrolase SARM1(Mus musculus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Affinity DataIC50: 318nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNicotinamide/nicotinic acid mononucleotide adenylyltransferase 1(Homo sapiens)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2(Homo sapiens)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660042BDBM50660042(CHEMBL6146508)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed