BDBM50660020 CHEMBL6132970

SMILES CCN(C)C(=O)Oc1ccc(C(=O)N2CCC(Cc3ccccc3)CC2)cc1OC

InChI Key InChIKey=MYFMLWCQCGTXER-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50660020   

TargetCholinesterase(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660020BDBM50660020(CHEMBL6132970)
Affinity DataIC50: 834nMAssay Description:Inhibition of human BuChE using BTCI as substrate incubated for 33 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCholinesterase(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660020BDBM50660020(CHEMBL6132970)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of human BuChE using BTCI as substrate incubated for 3 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660020BDBM50660020(CHEMBL6132970)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human serum DPP-IV using GP-BAN as substrate preincubated for 3 mins followed by substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProthrombin(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660020BDBM50660020(CHEMBL6132970)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Thrombin using Z-GGRAMC as substrate preincubated for 3 mins followed by substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660020BDBM50660020(CHEMBL6132970)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Notum using OPTS as substrate preincubated for 1 min followed by substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660020BDBM50660020(CHEMBL6132970)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human AChE using ATCI as substrate incubated for 3 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed