BDBM50659456 CHEMBL6169933

SMILES CC(C)N1c2cc(Nc3nccc(Nc4nn(C)c5ccccc45)n3)ccc2N(C)C(=O)[C@H]1C

InChI Key InChIKey=WGUSFXWMQGYBMI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50659456   

TargetBromodomain-containing protein 4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659456BDBM50659456(CHEMBL6169933)
Affinity DataIC50: 14nMAssay Description:Inhibition of BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) extracted from Escherichia coli BL21 (D3) codon plus RIL cells incubated for 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659456BDBM50659456(CHEMBL6169933)
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD2 bromodomain 1 (67 to 200 residues) (unknown origin) extracted from Escherichia coli BL21 (D3) codon plus RIL cells incubated for 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659456BDBM50659456(CHEMBL6169933)
Affinity DataIC50: 178nMAssay Description:Inhibition of BRD4 bromodomain 2 (332 to 460 residues) (unknown origin) extracted from Escherichia coli BL21 (D3) codon plus RIL cells incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659456BDBM50659456(CHEMBL6169933)
Affinity DataIC50: 233nMAssay Description:Inhibition of BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) extracted from Escherichia coli BL21 (D3) codon plus RIL cells incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659456BDBM50659456(CHEMBL6169933)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EP300 (1039 to 1161 residues) (unknown origin) extracted from Escherichia coli BL21 (D3) codon plus RIL cells incubated for 4 hrs by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed