BDBM50659395 CHEMBL6169853

SMILES O=C(/C=C/c1ccccc1)Nc1ccc2sc(NCN3C(=O)CSC3=O)nc2c1

InChI Key InChIKey=FNPMPZHLRIIPHE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50659395   

TargetProstaglandin G/H synthase 2(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659395BDBM50659395(CHEMBL6169853)
Affinity DataIC50: 107nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and in presence of TMPD preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659395BDBM50659395(CHEMBL6169853)
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-LOX (unknown origin) using linoleic acid as substrate incubated for 5 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659395BDBM50659395(CHEMBL6169853)
Affinity DataIC50: 9.07E+3nMAssay Description:Inhibition of Electric eel AChE using acetylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659395BDBM50659395(CHEMBL6169853)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of human MAO-B using tyramine/benzylamine as substrate measured after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659395BDBM50659395(CHEMBL6169853)
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of human MAO-A using tyramine/benzylamine as substrate measured after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed