BDBM50659386 CHEMBL6160940

SMILES O=C(CN1C(=O)S/C(=C\c2c[nH]c3ccccc23)C1=O)Nc1nc2ccccc2s1

InChI Key InChIKey=NJTXRMNNSUDISW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50659386   

TargetAmine oxidase [flavin-containing] B(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659386BDBM50659386(CHEMBL6160940)
Affinity DataIC50: 39nMAssay Description:Inhibition of human MAO-B using tyramine/benzylamine as substrate measured after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659386BDBM50659386(CHEMBL6160940)
Affinity DataIC50: 450nMAssay Description:Inhibition of Electric eel AChE using acetylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659386BDBM50659386(CHEMBL6160940)
Affinity DataIC50: 590nMAssay Description:Inhibition of 5-LOX (unknown origin) using linoleic acid as substrate incubated for 5 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBeta-secretase 1(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659386BDBM50659386(CHEMBL6160940)
Affinity DataIC50: 910nMAssay Description:Inhibition of BACE-1 (unknown origin) 667-676- (2, 4-dinitrophenyl) Lys-Arg-Arg amide trifluoroacetate as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659386BDBM50659386(CHEMBL6160940)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of human MAO-A using tyramine/benzylamine as substrate measured after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659386BDBM50659386(CHEMBL6160940)
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and in presence of TMPD preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659386BDBM50659386(CHEMBL6160940)
Affinity DataIC50: 4.25E+4nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and in presence of TMPD preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed