BDBM50659383 CHEMBL6133704

SMILES Cc1c(-c2nnc(S)n2N=Cc2ccc(F)cc2)cnn1-c1ccc(S(C)(=O)=O)cc1

InChI Key InChIKey=LLTQIUGVKZYADU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50659383   

TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 76nMAssay Description:Inhibition of human EGFR T790M mutant by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 121nMAssay Description:Inhibition of human wild-type EGFR by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed