BDBM50659307 CHEMBL6171514

SMILES CCCCN1C(=O)CC(c2ccccc2)n2nc(-c3ccc(OC)cc3)nc21

InChI Key InChIKey=CGXPRGVYMCUJJM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50659307   

TargetGABA-A receptor; alpha-1/beta-2/gamma-2(Human)
Qingdao University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659307BDBM50659307(CHEMBL6171514)
Affinity DataEC50:  1.24E+3nMAssay Description:Potentiation of recombinant human alpha1/beta2/gamma2 GABA receptor expressed in T-REX-CHO cells assessed as increase in current amplitude by whole-c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Qingdao University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659307BDBM50659307(CHEMBL6171514)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of Nav 1.2 (unknown origin) expressed in HEK293 cells at -20 mV to -120 mV holding potential under inactivation state by whole-cell patch ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed