BDBM50659087 CHEMBL6161199

SMILES O=C(N[C@H](Cn1nccn1)C(F)(F)CO)c1cccc(F)c1-c1cc(-c2ccc(F)cc2)[nH]n1

InChI Key InChIKey=UEPRFRHXFVOHAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50659087   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659087BDBM50659087(CHEMBL6161199)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at rat TRPM8 transfected in HEK293T cells assessed as reduction in intracellular Ca2+ level Fluo-4 dye based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659087BDBM50659087(CHEMBL6161199)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as inhibition of intracellular Ca2+ level by Fluo-4 dye based fluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed