BDBM50659033 CHEMBL6147790

SMILES Cc1c(C(=O)O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c(=O)n1-c1ccc2c(c1)oc(=O)n2C

InChI Key InChIKey=YUDINNSDBLNGSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50659033   

TargetChymase(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659033BDBM50659033(CHEMBL6147790)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant chymase using Abz-HPFHL-Lys(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetChymase(Canis lupus familiaris)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659033BDBM50659033(CHEMBL6147790)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant dog chymase using Abz-HPFHL-Lys(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed