BDBM50658582 CHEMBL6167008

SMILES CCn1c(N[C@@H]2CCN(C(=O)c3ccc(-c4ccccc4)cn3)C2)nc(C2CC2)c(Cl)c1=O

InChI Key InChIKey=HHARCTVDZIAPSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50658582   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658582BDBM50658582(CHEMBL6167008)
Affinity DataIC50: 3nMAssay Description:Inhibition of TEV protease cleavable N-terminal His6/Thioredoxin-tagged human recombinant PDE7A1 (47 to 482 residues) expressed in baculovirus-infect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHigh affinity 3',5'-cyclic-AMP phosphodiesterase 7A(Rattus norvegicus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658582BDBM50658582(CHEMBL6167008)
Affinity DataIC50: 390nMAssay Description:Inhibition of PDE7A in rat UMR-106 cells transfected with ECR5 reporter plasmid assessed as inhibition of ECR5 enhancer activity incubated for 1 day ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658582BDBM50658582(CHEMBL6167008)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant human PDE4D catalytic domain expressed in Escherichia coli using cAMP as substate incubated for 10 mins by chemilumin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed