BDBM50658547 CHEMBL6148436

SMILES Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CCCCCCC(=O)NO)cc3)ccc2N2CCN(C)CC2)c1Cl

InChI Key InChIKey=VWHCOMLIJVEQGT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50658547   

TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 35nMAssay Description:Inhibition of HDAC3 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 99nMAssay Description:Inhibition of HDAC2 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 392nMAssay Description:Inhibition of MLL1 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 7.61E+3nMAssay Description:Inhibition of HDAC11 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658547BDBM50658547(CHEMBL6148436)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed