BDBM50658497 CHEMBL6148030

SMILES CS(=O)(=O)n1ccc(C(=O)NCC(=O)Nc2nc(-c3cccc(N4CCCC4)n3)cs2)c1

InChI Key InChIKey=VUOGCEZTGZAUGI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50658497   

TargetProbable global transcription activator SNF2L2(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658497BDBM50658497(CHEMBL6148030)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length C-terminal his6/FLAG-tagged BRM (unknown origin) (1 to 1590 residues) incubated for 2 hrs by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTranscription activator BRG1(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658497BDBM50658497(CHEMBL6148030)
Affinity DataIC50: 18nMAssay Description:Inhibition of C-terminal his6/FLAG-tagged BRG1 (unknown origin) (1 to 1647 residues) incubated for 2 hrs by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTranscription activator BRG1(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658497BDBM50658497(CHEMBL6148030)
Affinity DataIC50: 167nMAssay Description:Inhibition of BRG1 in human MDA-MB-231 cells co-transfected with MMTV incubated for 6 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProbable global transcription activator SNF2L2(Human)
Foghorn Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658497BDBM50658497(CHEMBL6148030)
Affinity DataIC50: 173nMAssay Description:Inhibition of BRM in human A549 cells co-transfected with MMTV incubated for 6 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed