BDBM50658488 CHEMBL6133855
SMILES CS(=O)(=O)n1ccc(C(=O)NCC(=O)Nc2nc(-c3cccc(-c4ccncc4)n3)cs2)c1
InChI Key InChIKey=ZCMQEWBFUMSPCT-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50658488
Affinity DataIC50: 3nMAssay Description:Inhibition of full length C-terminal his6/FLAG-tagged BRM (unknown origin) (1 to 1590 residues) incubated for 2 hrs by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of C-terminal his6/FLAG-tagged BRG1 (unknown origin) (1 to 1647 residues) incubated for 2 hrs by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of BRG1 in human MDA-MB-231 cells co-transfected with MMTV incubated for 6 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 266nMAssay Description:Inhibition of BRM in human A549 cells co-transfected with MMTV incubated for 6 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetChromodomain-helicase-DNA-binding protein 4(Homo sapiens)
Foghorn Therapeutics
Curated by ChEMBL
Foghorn Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged,C-terminal his6-tagged CHD4 (unknown origin) (1 to 1912 residues) incubated for 1 hr by ADP-glo reagent based as...More data for this Ligand-Target Pair