BDBM50658342 CHEMBL6161081

SMILES COc1ccc(-c2nc3cnc(NCC(F)(F)F)nc3n(-c3ccc(Br)cc3)c2=O)cc1

InChI Key InChIKey=SDVDXTVLSRQCOO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50658342   

TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658342BDBM50658342(CHEMBL6161081)
Affinity DataIC50: 151nMAssay Description:Inhibition of MAT2A (unknown origin) using L-methionine and ATP as substrate preincubated with compound for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed