BDBM50657850 CHEMBL6142455

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2c(=O)n(CC(F)F)c(C)nc21

InChI Key InChIKey=VPNUHBRRZRYORN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657850   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657850BDBM50657850(CHEMBL6142455)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to recombinant human PKMYT1 incubated for15 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657850BDBM50657850(CHEMBL6142455)
Affinity DataIC50: 80nMAssay Description:Inhibition of CDK1 phosphorylation in human HCC1569 cells incubated for 6 hrs by In-cell Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed