BDBM50657843 CHEMBL6150434

SMILES COc1ccc2c(CN[C@H]3CC[C@@H](Nc4ncc(C(=O)NO)cn4)CC3)cn(C)c2c1

InChI Key InChIKey=PJRJBKFEYSAAPC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50657843   

TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human HDAC2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human HDAC8 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human SIRT2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed