BDBM50657755 CHEMBL6143596

SMILES CCS(=O)(=O)c1nc(S(=O)(=O)c2ccccc2C#N)c(N2CCN(C)C(=O)[C@@H]2C)s1

InChI Key InChIKey=BDNSEXWEXUBTRZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657755   

TargetNuclear factor erythroid 2-related factor 2(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657755BDBM50657755(CHEMBL6143596)
Affinity DataEC50:  3.5nMAssay Description:Inhibition of Keap1/Nrf2 protein-protein interaction in human HepG2 cells transfected with beta-lactamase under the control of ARE incubated for 16 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657755BDBM50657755(CHEMBL6143596)
Affinity DataEC50:  9.70nMAssay Description:Inhibition of human Keap1/PL-tagged human Nrf2 protein-protein interaction in human PathHunter U2OS Keap1-NRF2 Nuclear Translocation cells assessed a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed