BDBM50657742 CHEMBL6159634

SMILES CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(-c3cccn(C)c3=O)cc2)c(N2CCN(C)C(=O)C2)s1

InChI Key InChIKey=IVNPDVOTJJUZMR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657742   

TargetNuclear factor erythroid 2-related factor 2(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657742BDBM50657742(CHEMBL6159634)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of human Keap1/PL-tagged human Nrf2 protein-protein interaction in human PathHunter U2OS Keap1-NRF2 Nuclear Translocation cells assessed a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657742BDBM50657742(CHEMBL6159634)
Affinity DataEC50:  5.20nMAssay Description:Inhibition of Keap1/Nrf2 protein-protein interaction in human HepG2 cells transfected with beta-lactamase under the control of ARE incubated for 16 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed