BDBM50657525 CHEMBL6146345

SMILES CN1C(=O)C[C@H]2CC3(CC3)CN2C(=O)c2cncc(c2)NCCCCCCNC(=O)[C@H]1Cc1ccc(Cl)cc1Cl

InChI Key InChIKey=SZWKBXYVDYHRDG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657525   

TargetReplicase polyprotein 1ab(2019-nCoV)
Arbutus Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657525BDBM50657525(CHEMBL6146345)
Affinity DataKi: <1nMAssay Description:Binding affinity to wild type SARS-CoV-2 main protease expressed in Escherichia coli assessed as inhibition constant using fluorogenic substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Arbutus Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657525BDBM50657525(CHEMBL6146345)
Affinity DataIC50: 6nMAssay Description:Inhibition of N/C terminal SARS-CoV-2 main protease extracted from Escherichia coli using EDANS-VNSTLQSGLRK-(Dabcyl)M as substrate preincubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed