BDBM50655510 CHEMBL5567336

SMILES c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)CN)O)O)N

InChI Key InChIKey=CPUNUFGYWFHFOF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50655510   

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655510BDBM50655510(CHEMBL5567336)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to SARS-CoV-2 nsp14 assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655510BDBM50655510(CHEMBL5567336)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 extracted from Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed