BDBM50655462 CHEMBL6146815

SMILES O=C(Nc1ccc(Cc2nc3cc(C(F)(F)F)ccc3[nH]2)cc1)c1ccccc1F

InChI Key InChIKey=LBFKWDZYIQASBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50655462   

TargetProstaglandin E synthase(Human)
Gazi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655462BDBM50655462(CHEMBL6146815)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-beta induced PGE2 release preincubated for 15 mins followed by PGH2 addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed