BDBM50655398 CHEMBL6133873

SMILES O=C(CCCCCONC(=O)c1nc(-c2ccc(N3CCCC3)cc2)cs1)NO

InChI Key InChIKey=KBLCAMIJGLOLHZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50655398   

TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant Human HDAC3/NCOR2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human recombinant HDAC11 using Boc-Lys(trifluoroacetyl)-AMC) as fluorogenic substrate incubated for 90 mins by fluorescence based analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC4 using Boc-Lys(trifluoroacetyl)-AMC) as fluorogenic substrate incubated for 90 mins by fluorescence based analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed