BDBM50655389 CHEMBL6146648

SMILES COc1ccc(-c2csc(C(=O)NOCCCCCC(=O)NO)n2)cc1

InChI Key InChIKey=LAFLKLWIJPLLQL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50655389   

TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant Human HDAC3/NCOR2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human recombinant HDAC11 using Boc-Lys(trifluoroacetyl)-AMC) as fluorogenic substrate incubated for 90 mins by fluorescence based analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC4 using Boc-Lys(trifluoroacetyl)-AMC) as fluorogenic substrate incubated for 90 mins by fluorescence based analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed