BDBM50655342 CHEMBL6143775

SMILES Cc1cc(F)cc(C)c1Oc1ncc(C(C)(C)O)cc1-c1cn(C)c(=O)c2cc(-c3cnc(C4CCCC4)[nH]3)oc12

InChI Key InChIKey=LTXKPYBUBRXDOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50655342   

TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655342BDBM50655342(CHEMBL6143775)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of JAK2 in human A-431 cells assessed as reduction in IL-6-induced STAT3 phosphorylation preincubated for 1 hr followed by IL-6-stimulatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655342BDBM50655342(CHEMBL6143775)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655342BDBM50655342(CHEMBL6143775)
Affinity DataIC50: 379nMAssay Description:Inhibition of NKG2D (unknown origin)/ULBP6 (unknown origin) protein-protein interaction by cell-based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed