BDBM50653002 CHEMBL1643976

SMILES C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2Cl)c1

InChI Key InChIKey=APHGZZPEOCCYNO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50653002   

TargetEpidermal growth factor receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50653002(CHEMBL1643976)
Affinity DataIC50: 1.82E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50653002(CHEMBL1643976)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50653002(CHEMBL1643976)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50653002(CHEMBL1643976)
Affinity DataIC50: 1.98E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50653002(CHEMBL1643976)
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed