BDBM50652900 CHEMBL4746525

SMILES C[C@H]1CC(=O)Nc2cc(C(=O)NCCC3CC3)ccc2N1C(=O)N1CC2CC2C1

InChI Key InChIKey=CKFRXCBNKKOFGO-UHFFFAOYSA-N

Data  34 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50652900   

TargetNUAK family SNF1-like kinase 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDiacylglycerol kinase alpha(Mus musculus)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-6(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFYN-binding protein 1(Homo sapiens)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase I isoform alpha(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Affinity DataKd:  133nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Affinity DataIC50: 183nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Affinity DataKd:  97nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 13(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Affinity DataIC50: 8.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase I isoform gamma-3(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652900(CHEMBL4746525)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed